lansoprazole iv brand names and other generic formulations include:
methotrexate sodium inj brand names and other generic formulations include:
Mexate Inj, Mexate-aq Inj
lansoprazole iv and methotrexate sodium inj
lansoprazole iv increases levels of methotrexate sodium inj by reducing drug clearance through the kidneys. Increased risk of toxicity with higher doses.
lansoprazole iv and methotrexate sodium inj
lansoprazole iv increases levels of methotrexate sodium inj by decreasing renal clearance. Increased risk of toxicity with higher doses.
Check for more interactions with the Drug Interaction Checker
Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant