
lansoprazole iv brand names and other generic formulations include:
tacrolimus oral brand names and other generic formulations include:
Astagraf XL Oral, Envarsus XR Oral, Hecoria Oral, Prograf Oral
lansoprazole iv and tacrolimus oral
lansoprazole iv will increase the level or effect of tacrolimus oral by altering drug metabolism. Combination may increase tacrolimus concentration.
lansoprazole iv and tacrolimus oral
lansoprazole iv will increase the level or effect of tacrolimus oral by affecting hepatic enzyme CYP2C19 metabolism. Concomitant administration may increase tacrolimus whole blood concentrations, particularly in intermediate or poor metabolizers of CYP2C19
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant