Drug interactions with levothyroxine oral and pioglitazone-metformin oral

levothyroxine oral brand names and other generic formulations include:

Eltroxin Oral, Estre Oral, Estue Oral, Euthyrox Oral, Levo-T Oral, Levotabs Oral, Levothroid Oral, Levoxine Oral, Levoxyl Oral, L-Thyroxine Oral, L-Thyroxine Sodium Oral, Synthroid Oral, Synthrox Oral, Thyrox Oral, Tirosint Oral, Unithroid Oral

All generic drug interactions for levothyroxine oral (lists will include brand and generic names):

pioglitazone-metformin oral brand names and other generic formulations include:

Actoplus MET Oral, Actoplus Met XR Oral

All generic drug interactions for pioglitazone-metformin oral (lists will include brand and generic names):
Monitor CloselySignificant interaction possible (monitoring by your doctor required)

levothyroxine oral and pioglitazone-metformin oral

levothyroxine oral decreases effects of pioglitazone-metformin oral by opposing drug effects. This combination reduces the effect of metformin.

Patient Drug Interactions Source: RxList
© 2023 RxList, Inc.
Monitor CloselyUse Caution/Monitor.

levothyroxine oral and pioglitazone-metformin oral

levothyroxine oral decreases effects of pioglitazone-metformin oral by pharmacodynamic antagonism. Patient should be closely observed for loss of blood glucose control; when drugs are withdrawn from a patient receiving metformin, patient should be observed closely for hypoglycemia

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2023 WebMD, LLC.

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Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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