Drug interactions with lidocaine-prilocaine top and bupivacaine liposome (pf) local infiltration

lidocaine-prilocaine top brand names and other generic formulations include:

Emla Top, Emla/tegaderm Top, Livixil Pak Top, Lp Lite Pak Top, Relador Pak Plus Top, Relador Pak Top

All generic drug interactions for lidocaine-prilocaine top (lists will include brand and generic names):

bupivacaine liposome (pf) local infiltration brand names and other generic formulations include:

No brand names available

All generic drug interactions for bupivacaine liposome (pf) local infiltration (lists will include brand and generic names):
ContraindicatedNever use this combination of drugs because of high risk for dangerous interaction

lidocaine-prilocaine top and bupivacaine liposome (pf) local infiltration

lidocaine-prilocaine top increases toxicity of bupivacaine liposome (pf) local infiltration by Other mechanism. Do not use or mix local anesthetic drugs together; however some anesthetics may be used if certain time intervals pass.

Patient Drug Interactions Source: RxList
© 2023 RxList, Inc.
ContraindicatedContraindicated.

lidocaine-prilocaine top and bupivacaine liposome (pf) local infiltration

lidocaine-prilocaine top increases toxicity of bupivacaine liposome (pf) local infiltration by Other (see comment). Do not admix with other local nonbupivacaine-based local anesthetics; admixing results in a rapid increase in free (unencapsulated) bupivacaine; may administer after waiting at least 20 minutes following local administration of lidocaine

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2023 WebMD, LLC.

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Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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