
melphalan oral brand names and other generic formulations include:
No brand names available
tofacitinib oral brand names and other generic formulations include:
melphalan oral and tofacitinib oral
melphalan oral will increase the level or effect of tofacitinib oral by immune system suppression.
melphalan oral and tofacitinib oral
melphalan oral will increase the level or effect of tofacitinib oral by immunosuppressive effects; risk of infection. Avoid use in combination with potent immunosuppressants; concurrent use with antirheumatic doses of methotrexate or nonbiologic disease modifying antirheumatic drugs (DMARDs) is permitted. Agents considered as potent immunosuppressants are not specified, but lower corticosteroid doses (ie, equivalent to prednisone 10 mg/day or less), leflunomide, and antirheumatic doses of methotrexate were permitted in clinical studies.
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant