
morphine rect brand names and other generic formulations include:
Ms/s Rect, Rms Rect, Roxanol Rect
prasugrel oral brand names and other generic formulations include:
morphine rect and prasugrel oral
morphine rect will decrease the level or effect of prasugrel oral by reducing drug absorption from the stomach and intestine into the body when taken by mouth.
morphine rect and prasugrel oral
morphine rect will decrease the level or effect of prasugrel oral by inhibition of GI absorption. Applies only to oral form of both agents. Coadministration of opioid agonists delay and reduce the absorption of prasugrel’s active metabolite presumably because of slowed gastric emptying. Consider using a parenteral antiplatelet agent in acute coronary syndrome patients requiring coadministration of morphine or other opioid agonists. Risks associated with other opioids are unknown.
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant