
netupitant-palonosetron oral brand names and other generic formulations include:
Akynzeo Oral
irinotecan iv brand names and other generic formulations include:
netupitant-palonosetron oral and irinotecan iv
netupitant-palonosetron oral will increase the level or effect of irinotecan iv by altering drug metabolism.
netupitant-palonosetron oral and irinotecan iv
netupitant-palonosetron oral will increase the level or effect of irinotecan iv by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant