
nicardipine iv brand names and other generic formulations include:
Cardene IV
ruxolitinib oral brand names and other generic formulations include:
nicardipine iv and ruxolitinib oral
nicardipine iv will increase the level or effect of ruxolitinib oral by altering drug metabolism. May increase drug blood levels.
nicardipine iv and ruxolitinib oral
nicardipine iv will increase the level or effect of ruxolitinib oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Reduce ruxolitinib starting dose to 10 mg BID with platelet count 100 X 10^9/L or more and concurrent use of strong CYP3A4 inhibitors; avoid with platelet counts <100 X 10^9/L
Check for more interactions with the Drug Interaction Checker
Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant