
nicardipine iv brand names and other generic formulations include:
Cardene IV
tadalafil oral brand names and other generic formulations include:
Adcirca Oral, Cialis Oral
nicardipine iv and tadalafil oral
nicardipine iv will increase the level or effect of tadalafil oral by altering drug metabolism. Avoid use with CYP3A4 inhibitors, they may increase systemic exposure to tadalafil; significantly increased levels may result in significant adverse events including severe hypotension, syncope, visual changes, and priapism.
nicardipine iv and tadalafil oral
nicardipine iv will increase the level or effect of tadalafil oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. CYP3A4 inhibitors may reduce tadalafil clearance increasing systemic exposure to tadalafil; significantly increased levels may result in significant adverse events including severe hypotension, syncope, visual changes, and priapism.
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant