Drug interactions with nilotinib oral and afatinib oral

nilotinib oral brand names and other generic formulations include:

Tasigna Oral

All generic drug interactions for nilotinib oral (lists will include brand and generic names):

afatinib oral brand names and other generic formulations include:

Gilotrif Oral

All generic drug interactions for afatinib oral (lists will include brand and generic names):
Serious - Use AlternativePotential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

nilotinib oral and afatinib oral

nilotinib oral increases levels of afatinib oral by affects how the drug is eliminated from the body (via what is known as the P-glycoprotein [MDR1] transporter). Your doctor may reduce afatinib daily dose by 10 mg if it is not tolerated when taken in this combination.

Patient Drug Interactions Source: RxList
© 2023 RxList, Inc.
Serious - Use AlternativeAvoid or Use Alternate Drug.

nilotinib oral and afatinib oral

nilotinib oral increases levels of afatinib oral by P-glycoprotein (MDR1) efflux transporter. Reduce afatinib daily dose by 10 mg if not tolerated when coadministered with P-gp inhibitors

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2023 WebMD, LLC.

Check for more interactions with the Drug Interaction Checker

Check Now ยป

Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

Health Solutions From Our Sponsors