Drug interactions with omeprazole oral and methotrexate sodium inj

omeprazole oral brand names and other generic formulations include:

No brand names available

All generic drug interactions for omeprazole oral (lists will include brand and generic names):

methotrexate sodium inj brand names and other generic formulations include:

Mexate Inj, Mexate-aq Inj

All generic drug interactions for methotrexate sodium inj (lists will include brand and generic names):
Monitor CloselySignificant interaction possible (monitoring by your doctor required)

omeprazole oral and methotrexate sodium inj

omeprazole oral increases levels of methotrexate sodium inj by reducing drug clearance through the kidneys. Your doctor may decide that you need to temporarily stop taking the proton pump inhibitor.

Patient Drug Interactions Source: RxList
© 2023 RxList, Inc.
Monitor CloselyUse Caution/Monitor.

omeprazole oral and methotrexate sodium inj

omeprazole oral increases levels of methotrexate sodium inj by decreasing renal clearance. Temporary withdrawal of PPI may be considered in some patients.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2023 WebMD, LLC.

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Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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