omeprazole oral brand names and other generic formulations include:
No brand names available
tofacitinib oral brand names and other generic formulations include:
omeprazole oral and tofacitinib oral
omeprazole oral increases levels of tofacitinib oral by altering drug metabolism. Blood levels of tofacitinib may be affected but there is no recommended dose adjustment.
omeprazole oral and tofacitinib oral
omeprazole oral increases levels of tofacitinib oral by affecting hepatic enzyme CYP2C19 metabolism. No specific dose adjustment recommended when tofacitinib coadministered with potent CYP2C19 inhibitors; decrease tofacitinib dose if coadministered with both moderate CYP3A4 and potent CYP2C19 inhibitors
Check for more interactions with the Drug Interaction Checker
Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant