Drug interactions with ondansetron oral and panobinostat oral

ondansetron oral brand names and other generic formulations include:

Zofran ODT Oral, Zuplenz Oral

All generic drug interactions for ondansetron oral (lists will include brand and generic names):

panobinostat oral brand names and other generic formulations include:

Farydak Oral

All generic drug interactions for panobinostat oral (lists will include brand and generic names):
Monitor CloselyPotential for significant interaction (monitoring by your doctor is likely required)

ondansetron oral and panobinostat oral

ondansetron oral and panobinostat oral both increase causing a dangerous abnormal heart rhythm. Panobinostat is known to significantly increase risk of abnormal heart beats. Panobinostat prescribing information states taking in this combination is not recommended; however, drugs used to treat nausea and vomiting (antiemetics) known to increase abnormal heart beats (eg, dolasetron, granisetron, ondansetron) can be used with frequent ECG monitoring.

Patient Drug Interactions Source: RxList
© 2023 RxList, Inc.
Monitor CloselyModify Therapy/Monitor Closely.

ondansetron oral and panobinostat oral

ondansetron oral and panobinostat oral both increase QTc interval. Panobinostat is known to significantly prolong QT interval. Panobinostat prescribing information states use with drugs known to prolong QTc is not recommended; however, antiemetic drugs known to prolong QTc (eg, dolasetron, granisetron, ondansetron) can be used with frequent ECG monitoring.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2023 WebMD, LLC.

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Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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