Drug interactions with oxycodone-acetaminophen oral and paroxetine oral

oxycodone-acetaminophen oral brand names and other generic formulations include:

ALCET Oral, Endocet Oral, Lynox Oral, Magnacet Oral, Narvox Oral, Percocet Oral, Perloxx Oral, Primalev Oral, Primlev Oral, Roxicet Oral, Tylox Oral, Xartemis XR Oral, Xolox Oral

All generic drug interactions for oxycodone-acetaminophen oral (lists will include brand and generic names):

paroxetine oral brand names and other generic formulations include:

Paxil CR Oral, Paxil Oral

All generic drug interactions for paroxetine oral (lists will include brand and generic names):
Monitor CloselyPotential for significant interaction (monitoring by your doctor is likely required)

oxycodone-acetaminophen oral and paroxetine oral

oxycodone-acetaminophen oral increases effects of paroxetine oral by added drug effects. The combination increases the risk of serotonin syndrome, a serious side effect that can cause death.

Patient Drug Interactions Source: RxList
© 2023 RxList, Inc.
Monitor CloselyModify Therapy/Monitor Closely.

oxycodone-acetaminophen oral and paroxetine oral

oxycodone-acetaminophen oral increases effects of paroxetine oral by pharmacodynamic synergism. Opioids may enhance the serotonergic effects of SSRIs and increase risk for serotonergic syndrome

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2023 WebMD, LLC.

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Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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