Drug interactions with phenobarbital oral and darunavir-cobicistat oral

phenobarbital oral brand names and other generic formulations include:

Barbita Oral, Neuroval Oral, Sk-Phenobarbital Oral, Solfoton Oral

All generic drug interactions for phenobarbital oral (lists will include brand and generic names):

darunavir-cobicistat oral brand names and other generic formulations include:

Prezcobix Oral

All generic drug interactions for darunavir-cobicistat oral (lists will include brand and generic names):
ContraindicatedNever use this combination of drugs because of high risk for dangerous interaction

phenobarbital oral and darunavir-cobicistat oral

phenobarbital oral will decrease the level or effect of darunavir-cobicistat oral by altering drug metabolism.

Patient Drug Interactions Source: RxList
© 2023 RxList, Inc.
ContraindicatedContraindicated.

phenobarbital oral and darunavir-cobicistat oral

phenobarbital oral will decrease the level or effect of darunavir-cobicistat oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Coadministration with phenobarbital may result in loss of therapeutic effect and development of resistance to darunavir

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2023 WebMD, LLC.

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Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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