Drug interactions with pioglitazone-metformin oral and linagliptin oral

pioglitazone-metformin oral brand names and other generic formulations include:

Actoplus MET Oral, Actoplus Met XR Oral

All generic drug interactions for pioglitazone-metformin oral (lists will include brand and generic names):

linagliptin oral brand names and other generic formulations include:

Tradjenta Oral

All generic drug interactions for linagliptin oral (lists will include brand and generic names):
Monitor CloselySignificant interaction possible (monitoring by your doctor required)

pioglitazone-metformin oral and linagliptin oral

pioglitazone-metformin oral will increase the level or effect of linagliptin oral by altering drug metabolism. Use of alternative treatments is strongly recommended when linagliptin is to be taken in this combination.

Patient Drug Interactions Source: RxList
© 2023 RxList, Inc.
Monitor CloselyUse Caution/Monitor.

pioglitazone-metformin oral and linagliptin oral

pioglitazone-metformin oral will increase the level or effect of linagliptin oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use of alternative treatments is strongly recommended when linagliptin is to be administered with a CYP3A4 inducer

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2023 WebMD, LLC.

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Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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