
pioglitazone-metformin oral brand names and other generic formulations include:
Actoplus MET Oral, Actoplus Met XR Oral
pravastatin oral brand names and other generic formulations include:
pioglitazone-metformin oral and pravastatin oral
pioglitazone-metformin oral increases toxicity of pravastatin oral by Other mechanism. Combination increases risk of muscle damage.
pioglitazone-metformin oral and pravastatin oral
pioglitazone-metformin oral increases toxicity of pravastatin oral by Other (see comment). OATP1B1 inhibitors may increase risk of myopathy
Check for more interactions with the Drug Interaction Checker
Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant