
pioglitazone-metformin oral brand names and other generic formulations include:
Actoplus MET Oral, Actoplus Met XR Oral
trospium oral brand names and other generic formulations include:
Sanctura Oral, Sanctura XR Oral
pioglitazone-metformin oral and trospium oral
pioglitazone-metformin oral will decrease the level or effect of trospium oral by increasing the elimination of the drug through the kidney. Combination reduces trospium exposure.
pioglitazone-metformin oral and trospium oral
pioglitazone-metformin oral will decrease the level or effect of trospium oral by increasing renal clearance. Coadministration reduced steady state trospium systemic exposure (decreased AUC and Cmax) by competing for renal tubular secretion
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant