Drug interactions with ponatinib oral and edoxaban oral

ponatinib oral brand names and other generic formulations include:

Iclusig Oral

All generic drug interactions for ponatinib oral (lists will include brand and generic names):

edoxaban oral brand names and other generic formulations include:

Savaysa Oral

All generic drug interactions for edoxaban oral (lists will include brand and generic names):
Serious - Use AlternativePotential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

ponatinib oral and edoxaban oral

ponatinib oral will increase the level or effect of edoxaban oral by affects how the drug is eliminated from the body (via what is known as the P-glycoprotein [MDR1] transporter). Your doctor may consider adjusting your dosage.

Patient Drug Interactions Source: RxList
© 2023 RxList, Inc.
Serious - Use AlternativeAvoid or Use Alternate Drug.

ponatinib oral and edoxaban oral

ponatinib oral will increase the level or effect of edoxaban oral by P-glycoprotein (MDR1) efflux transporter. Dose adjustment may be required with strong P-gp inhibitors. DVT/PE treatment: Decrease dose to 30 mg PO once daily. NVAF: No dose reduction recommended

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2023 WebMD, LLC.

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Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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