Drug interactions with primidone oral and estradiol valerate-dienogest oral

primidone oral brand names and other generic formulations include:

Mysoline Oral, Sterasoline Oral

All generic drug interactions for primidone oral (lists will include brand and generic names):

estradiol valerate-dienogest oral brand names and other generic formulations include:

Natazia Oral

All generic drug interactions for estradiol valerate-dienogest oral (lists will include brand and generic names):
ContraindicatedNever use this combination of drugs because of high risk for dangerous interaction

primidone oral and estradiol valerate-dienogest oral

primidone oral will decrease the level or effect of estradiol valerate-dienogest oral by altering drug metabolism. Decreased level or effect of estradiol valerate/dienogest. Avoid combination and do not use estradiol valerate/dienogest for 28 days after stopping the drug.

Patient Drug Interactions Source: RxList
© 2023 RxList, Inc.
ContraindicatedContraindicated.

primidone oral and estradiol valerate-dienogest oral

primidone oral will decrease the level or effect of estradiol valerate-dienogest oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Women should not choose estradiol valerate/dienogest as their contraceptive while using strong CYP3A4 inducers due to potential decrease in contraceptive efficacy. Estradiol valerate/dienogest should not be used for at least 28 days after discontinuation of the inducer due to possibility of decreased contraceptive efficacy.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2023 WebMD, LLC.

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Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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