Drug interactions with primidone oral and vandetanib oral

primidone oral brand names and other generic formulations include:

Mysoline Oral, Sterasoline Oral

All generic drug interactions for primidone oral (lists will include brand and generic names):

vandetanib oral brand names and other generic formulations include:

Caprelsa Oral

All generic drug interactions for vandetanib oral (lists will include brand and generic names):
ContraindicatedNever use this combination of drugs because of high risk for dangerous interaction

primidone oral and vandetanib oral

primidone oral decreases levels of vandetanib oral by altering drug metabolism. Vandetanib blood levels may be reduced by 40%.

Patient Drug Interactions Source: RxList
© 2023 RxList, Inc.
ContraindicatedContraindicated.

primidone oral and vandetanib oral

primidone oral decreases levels of vandetanib oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid coadministration with potent CYP3A4 inducers; these drugs reduce exposure to vandetanib by up to 40%

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2023 WebMD, LLC.

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Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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