
promethazine-phenylephrine-codeine oral brand names and other generic formulations include:
Chemergan VC With Codeine Oral, Mallergan-VC With Codeine Oral, M-Phen Oral, Para-Hist At Oral, Phenergan VC-Codeine Oral, Promethazine VC-Codeine Oral
perphenazine inj brand names and other generic formulations include:
Trilafon Inj
promethazine-phenylephrine-codeine oral and perphenazine inj
promethazine-phenylephrine-codeine oral , perphenazine inj unspecified interaction mechanism.
promethazine-phenylephrine-codeine oral and perphenazine inj
promethazine-phenylephrine-codeine oral , perphenazine inj unspecified interaction mechanism. Serotonin modulators may enhance dopamine blockade, possibly increasing the risk for neuroleptic malignant syndrome. Antipsychotics may enhance serotonergic effect of serotonin modulators, which may result in serotonin syndrome. Monitor for evidence of serotonin toxicity (eg, mental status changes, autonomic instability, and neuromuscular hyperactivity) or neuroleptic malignant syndrome (eg, hyperthermia, muscle rigidity, autonomic dysfunction).
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant