
rabeprazole oral brand names and other generic formulations include:
Aciphex Oral, AcipHex Sprinkle Oral
budesonide oral brand names and other generic formulations include:
Entocort EC Oral, Uceris Oral
rabeprazole oral and budesonide oral
rabeprazole oral decreases effects of budesonide oral by reducing stomach acidity. This interaction may occur when both drugs are taken by mouth. Drugs that reduce stomach acidity may reduce the absorption of enteric-coated budesonide.
rabeprazole oral and budesonide oral
rabeprazole oral decreases effects of budesonide oral by increasing gastric pH. Applies only to oral form of both agents. Enteric-coated budesonide dissolves at pH >5.5. Also, dissolution of extended-release budesonide tablets is pH dependent. Coadministration with drugs that increase gastric pH may cause these budesonide products to prematurely dissolve, and possibly affect release properties and absorption of the drug in the duodenum.
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant