Drug interactions with rabeprazole oral and nilotinib oral

rabeprazole oral brand names and other generic formulations include:

Aciphex Oral, AcipHex Sprinkle Oral

All generic drug interactions for rabeprazole oral (lists will include brand and generic names):

nilotinib oral brand names and other generic formulations include:

Tasigna Oral

All generic drug interactions for nilotinib oral (lists will include brand and generic names):
Serious - Use AlternativePotential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

rabeprazole oral and nilotinib oral

rabeprazole oral will decrease the level or effect of nilotinib oral by reducing stomach acidity. This interaction may occur when both drugs are taken by mouth. Dexlansoprazole reduces absorption of nilotinib, possible reducing the effect of nilotinib.

Patient Drug Interactions Source: RxList
© 2023 RxList, Inc.
Serious - Use AlternativeAvoid or Use Alternate Drug.

rabeprazole oral and nilotinib oral

rabeprazole oral will decrease the level or effect of nilotinib oral by increasing gastric pH. Applies only to oral form of both agents. Nilotinib has a pH-dependent solubility and solubility is decreased at higher pH; separating doses may not eliminate this effect because of PPI extended duration of action

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2023 WebMD, LLC.

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Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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