Drug interactions with regorafenib oral and chlorothiazide oral

regorafenib oral brand names and other generic formulations include:

Stivarga Oral

All generic drug interactions for regorafenib oral (lists will include brand and generic names):

chlorothiazide oral brand names and other generic formulations include:

Chlorulan Oral, Dithirex Oral, Diurigen Oral, Diuril Oral, Kenuril 250 Oral, Kenuril 500 Oral, Sk-Chlorothiazide Oral

All generic drug interactions for chlorothiazide oral (lists will include brand and generic names):
Monitor CloselyPotential for significant interaction (monitoring by your doctor is likely required)

regorafenib oral and chlorothiazide oral

regorafenib oral will increase the level or effect of chlorothiazide oral by Other mechanism. This combination may increase the risk of serious adverse effects.

Patient Drug Interactions Source: RxList
© 2023 RxList, Inc.
Monitor CloselyModify Therapy/Monitor Closely.

regorafenib oral and chlorothiazide oral

regorafenib oral will increase the level or effect of chlorothiazide oral by Other (see comment). Regorafenib likely inhibits BCRP (ABCG2) transport. Coadministration with a BCRP substrate may increase systemic exposure to the substrate and related toxicity.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2023 WebMD, LLC.

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Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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