
regorafenib oral brand names and other generic formulations include:
doxorubicin iv brand names and other generic formulations include:
Adriamycin IV, Adriamycin Pfs IV, Adriamycin Rdf IV, Rubex IV
regorafenib oral and doxorubicin iv
regorafenib oral will increase the level or effect of doxorubicin iv by Other mechanism. This combination may increase the risk of serious adverse effects.
regorafenib oral and doxorubicin iv
regorafenib oral will increase the level or effect of doxorubicin iv by Other (see comment). Regorafenib likely inhibits BCRP (ABCG2) transport. Coadministration with a BCRP substrate may increase systemic exposure to the substrate and related toxicity.
Check for more interactions with the Drug Interaction Checker
Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant