
regorafenib oral brand names and other generic formulations include:
irinotecan iv brand names and other generic formulations include:
regorafenib oral and irinotecan iv
regorafenib oral will increase the level or effect of irinotecan iv by slowing drug metabolism. Breakdown of irinotecan may be affected.
regorafenib oral and irinotecan iv
regorafenib oral will increase the level or effect of irinotecan iv by decreasing metabolism. Regorafenib may inhibit UGT1A1-mediated metabolism of irinotican and its metabolite
Check for more interactions with the Drug Interaction Checker
Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant