
rifampin-isoniazid oral brand names and other generic formulations include:
IsonaRif Oral, Rifamate Oral
bosentan oral brand names and other generic formulations include:
rifampin-isoniazid oral and bosentan oral
rifampin-isoniazid oral will decrease the level or effect of bosentan oral by altering drug metabolism.
rifampin-isoniazid oral and bosentan oral
rifampin-isoniazid oral will decrease the level or effect of bosentan oral by affecting hepatic enzyme CYP2C9/10 metabolism.
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant