Drug interactions with rifampin-isoniazid oral and dolutegravir oral

rifampin-isoniazid oral brand names and other generic formulations include:

IsonaRif Oral, Rifamate Oral

All generic drug interactions for rifampin-isoniazid oral (lists will include brand and generic names):

dolutegravir oral brand names and other generic formulations include:

Tivicay Oral

All generic drug interactions for dolutegravir oral (lists will include brand and generic names):
Serious - Use AlternativePotential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

rifampin-isoniazid oral and dolutegravir oral

rifampin-isoniazid oral will decrease the level or effect of dolutegravir oral by speeding up drug metabolism. Your doctor may increase your dolutegravir dose to 50 mg BID when taken in this combination (with strong UGT1A/CYP3A inducers).

Patient Drug Interactions Source: RxList
© 2023 RxList, Inc.
Serious - Use AlternativeAvoid or Use Alternate Drug.

rifampin-isoniazid oral and dolutegravir oral

rifampin-isoniazid oral will decrease the level or effect of dolutegravir oral by increasing metabolism. Increase dolutegravir dose to 50 mg BID when coadministered with strong UGT1A/CYP3A inducers

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2023 WebMD, LLC.

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Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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