
rifampin-isoniazid oral brand names and other generic formulations include:
IsonaRif Oral, Rifamate Oral
donepezil oral brand names and other generic formulations include:
Aricept ODT Oral, Aricept Oral
rifampin-isoniazid oral and donepezil oral
rifampin-isoniazid oral will decrease the level or effect of donepezil oral by altering drug metabolism.
rifampin-isoniazid oral and donepezil oral
rifampin-isoniazid oral will decrease the level or effect of donepezil oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant