
rifampin-isoniazid oral brand names and other generic formulations include:
IsonaRif Oral, Rifamate Oral
perampanel oral brand names and other generic formulations include:
Fycompa Oral
rifampin-isoniazid oral and perampanel oral
rifampin-isoniazid oral will decrease the level or effect of perampanel oral by altering drug metabolism. Increased dose of perampanel may be needed when taken in this combination.
rifampin-isoniazid oral and perampanel oral
rifampin-isoniazid oral will decrease the level or effect of perampanel oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Increased perampanel dose may be needed when coadministered
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant