
sodium bicarbonate iv brand names and other generic formulations include:
Neut IV
mesalamine oral brand names and other generic formulations include:
Apriso Oral, Asacol HD Oral, Asacol Oral, Delzicol Oral, Lialda Oral, Pentasa Oral
sodium bicarbonate iv and mesalamine oral
sodium bicarbonate iv , mesalamine oral Mechanism: affects how the kidney reabsorbs the drug in an nonacidic environment. Salicylate levels and side effects may increase or salicylate levels may decrease.
sodium bicarbonate iv and mesalamine oral
sodium bicarbonate iv , mesalamine oral Mechanism: passive renal tubular reabsorption due to increased pH. Salicylate levels increased at moderate doses; salicylate levels decreased at large doses (d/t increased renal excretion of unchanged salicylic acid).
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant