
tolbutamide oral brand names and other generic formulations include:
Icn-Tolam Oral, Oribetic Oral, Orinase Oral
canagliflozin-metformin oral brand names and other generic formulations include:
Invokamet Oral
tolbutamide oral and canagliflozin-metformin oral
tolbutamide oral , canagliflozin-metformin oral . Either increases the level of the other by added drug effects. Combination may increase risk of low blood glucose.
tolbutamide oral and canagliflozin-metformin oral
tolbutamide oral , canagliflozin-metformin oral . Either increases effects of the other by pharmacodynamic synergism. Consider a lower dose of insulin or insulin secretagogue to avoid hypoglycemia when coadministered with canagliflozin
Check for more interactions with the Drug Interaction Checker
Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant