
tolbutamide oral brand names and other generic formulations include:
Icn-Tolam Oral, Oribetic Oral, Orinase Oral
diclofenac sodium top brand names and other generic formulations include:
Pennsaid Top, Solaraze Top, Voltaren Top
tolbutamide oral and diclofenac sodium top
tolbutamide oral will increase the level or effect of diclofenac sodium top by altering drug metabolism. Do not exceed diclofenac dose of 50 mg BID.
tolbutamide oral and diclofenac sodium top
tolbutamide oral will increase the level or effect of diclofenac sodium top by affecting hepatic enzyme CYP2C9/10 metabolism. Do not exceed diclofenac dose of 50 mg BID
Check for more interactions with the Drug Interaction Checker
Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant