
tolbutamide oral brand names and other generic formulations include:
Icn-Tolam Oral, Oribetic Oral, Orinase Oral
lacosamide iv brand names and other generic formulations include:
Vimpat IV
tolbutamide oral and lacosamide iv
tolbutamide oral increases levels of lacosamide iv by altering drug metabolism. Your doctor may consider decreasing lacosamide dose.
tolbutamide oral and lacosamide iv
tolbutamide oral increases levels of lacosamide iv by affecting hepatic enzyme CYP2C9/10 metabolism. Consider decreasing lacosamide dose when coadministered with strong CYP2C9 inhibitors
Check for more interactions with the Drug Interaction Checker
Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant