voriconazole iv brand names and other generic formulations include:
Vfend IV IV
axitinib oral brand names and other generic formulations include:
voriconazole iv and axitinib oral
voriconazole iv increases levels of axitinib oral by altering drug metabolism. Only use with close monitoring; Reduce dose of axitinib by 50%.
voriconazole iv and axitinib oral
voriconazole iv increases levels of axitinib oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. If unable to avoid coadministration with strong CYP3A4 inhibitors, reduce axitinib dose by 50%
Check for more interactions with the Drug Interaction Checker
Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant