
voriconazole iv brand names and other generic formulations include:
Vfend IV IV
eliglustat oral brand names and other generic formulations include:
Cerdelga Oral
voriconazole iv and eliglustat oral
voriconazole iv will increase the level or effect of eliglustat oral by altering drug metabolism. Drug levels of eliglustat may be increased. Combination should be avoided.
voriconazole iv and eliglustat oral
voriconazole iv will increase the level or effect of eliglustat oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Strong CYP3A4 inhibitors are contraindicated with eliglustat poor or intermediate metabolizers; reduce eliglustat dose from 84 mg BID to 84 mg once daily in extensive metabolizers; eliglustat is contraindiated if strong or moderate CYP2D6 inhibitors are given concomitantly with strong or moderate CYP3A inhibitors
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant