
voriconazole iv brand names and other generic formulations include:
Vfend IV IV
fentanyl nasl brand names and other generic formulations include:
voriconazole iv and fentanyl nasl
voriconazole iv will increase the level or effect of fentanyl nasl by altering drug metabolism. Blood levels and side effects of fentanyl may increase. Consider reducing the dose of fentanyl and monitor for sedation and difficulty breathing.
voriconazole iv and fentanyl nasl
voriconazole iv will increase the level or effect of fentanyl nasl by affecting hepatic/intestinal enzyme CYP3A4 metabolism. If coadministration of CYP3A4 inhibitors with fentanyl is necessary, monitor patients for respiratory depression and sedation at frequent intervals and consider fentanyl dose adjustments until stable drug effects are achieved.
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant