
voriconazole oral brand names and other generic formulations include:
hydrocodone-ibuprofen oral brand names and other generic formulations include:
Ibudone Oral, Reprexain Oral, Vicoprofen Oral, Xylon 10 Oral
voriconazole oral and hydrocodone-ibuprofen oral
voriconazole oral will increase the level or effect of hydrocodone-ibuprofen oral by altering drug metabolism. Blood levels and side effects of hydrocodone may increase and can result in potentially life-threatening respiratory depression (difficulty breathing).
voriconazole oral and hydrocodone-ibuprofen oral
voriconazole oral will increase the level or effect of hydrocodone-ibuprofen oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Coadministration with CYP3A4 inhibitors may increase hydrocodone plasma concentrations and can result in potentially fatal respiratory depression
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant