
zileuton oral brand names and other generic formulations include:
suvorexant oral brand names and other generic formulations include:
Belsomra Oral
zileuton oral and suvorexant oral
zileuton oral will increase the level or effect of suvorexant oral by altering drug metabolism. Blood levels of suvorexant may increase.
zileuton oral and suvorexant oral
zileuton oral will increase the level or effect of suvorexant oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Decrease suvorexant starting dose to 5 mg HS if coadministered with moderate CYP3A4 inhibitors
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant