Duexis vs. Ibuprofen

Are Duexis and Ibuprofen the Same Thing?

Duexis (ibuprofen and famotidine) and ibuprofen are used to treat signs and symptoms of rheumatoid arthritis.

Duexis is used when there is a high risk of developing upper gastrointestinal ulcers.

Ibuprofen is also used to treat primary dysmenorrhea.

Both Duexis and ibuprofen are nonsteroidal anti-inflammatory drugs (NSAIDs) but Duexis also contains a histamine H2-receptor antagonist.

Brand names for ibuprofen include Advil, Motrin, NeoProfen, and Caldolor.

Ibuprofen is available over-the-counter (OTC) and as a generic.

Side effects of Duexis and ibuprofen that are similar include stomach pain, constipation, diarrhea, bloating, gas, heartburn, nausea, vomiting, dizziness, headache, or blurred vision.

Side effects of Duexis that are different from ibuprofen include upset stomach, throat irritation, changes in color vision, or back pain.

Side effects of ibuprofen that are different from Duexis include nervousness, skin itching or rash, or ringing in the ears.

Both Duexis and ibuprofen may interact with blood thinners, antidepressants, or cold, allergy, or pain medicines that contain nonsteroidal anti-inflammatory drugs (NSAIDs).

Ibuprofen may also interact with alcohol, aspirin, lithium, methotrexate, heart or blood pressure medications, diuretics (water pills), or steroids.

What Are Possible Side Effects of Duexis?

Common side effects of Duexis include:

  • stomach pain,
  • upset stomach,
  • constipation,
  • diarrhea,
  • bloating,
  • gas,
  • heartburn,
  • nausea,
  • vomiting,
  • dizziness,
  • headache,
  • throat irritation,
  • blurred vision,
  • changes in color vision, or
  • back pain.

Duexis can cause serious or fatal side effects including:

What Are Possible Side Effects of Ibuprofen?

Common side effects of Ibuprofen include:

  • stomach pain,
  • constipation,
  • diarrhea,
  • bloating,
  • gas,
  • heartburn,
  • nausea,
  • vomiting,
  • dizziness,
  • headache,
  • nervousness,
  • skin itching or rash,
  • blurred vision, or
  • ringing in the ears.

Other side effects of Ibuprofen may occur. Consult your physician if you experience any possible side effects of Ibuprofen.

What Is Duexis?

Duexis (ibuprofen and famotidine) is a combination of a nonsteroidal anti-inflammatory drug (NSAID) and a histamine H2-receptor antagonist used to treat signs and symptoms of rheumatoid arthritis and osteoarthritis and to decrease the risk of developing upper gastrointestinal ulcers.

What Is Ibuprofen?

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) indicated for relief of the signs and symptoms of rheumatoid arthritis and osteoarthritis, for relief of mild to moderate pain, and for treatment of primary dysmenorrhea. A generic formulation is available.

QUESTION

The term arthritis refers to stiffness in the joints. See Answer

What Drugs Interact With Duexis?

Duexis may interact with ACE-inhibitors. Duexis contains ibuprofen and may interact with anticoagulant medication such as Warfarin (Coumadin). Tell your doctor all medications you use. Duexis should not be given to women in late stages of pregnancy. There is potential for adverse reactions in nursing infants; consult your doctor before breastfeeding.

What Drugs Interact With Ibuprofen?

Ibuprofen may interact with other drugs. Tell your doctor all medications and supplements you use.

How Should Duexis Be Taken?

Duexis is dosed as 800 mg/26.6 mg tablets, taken orally, three times per day.

How Should Ibuprofen Be Taken?

The recommended dose of Motrin should be adjusted to suit individual patients needs but should not exceed 3200 mg in the total daily dose. Use of alcohol and smoking could increase side effects. Safe use of Motrin for use by children has not been established. It is not known whether ibuprofen is harmful to an unborn baby.

SLIDESHOW

What Is Rheumatoid Arthritis (RA)? Symptoms, Treatment, Diagnosis See Slideshow
Disclaimer

All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).

Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.

Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.

The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.

As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.

Any missing drug warnings or information does not in any way guarantee the safety, effectiveness, or the lack of adverse effects of any drug. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.

If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.

You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.

References
Horizon Pharma USA, Inc. Duexis Product Information.
https://www.duexis.com
Johnson & Johnson Consumer Inc. Motrin (Ibuprofen) Product Information.
https://www.motrin.com

Health Solutions From Our Sponsors