Duexis vs. Mobic

Are Duexis and Mobic the Same Thing?

Duexis (ibuprofen and famotidine) and Mobic (meloxicam) are used to treat signs and symptoms of rheumatoid arthritis and osteoarthritis.

Duexis is used when there is a high risk of developing upper gastrointestinal ulcers.

Both Duexis and Mobic are nonsteroidal anti-inflammatory drugs (NSAIDs) but Duexis also contains a histamine H2-receptor antagonist.

Side effects of Duexis and Mobic that are similar include upset stomach, diarrhea, bloating, gas, nausea, dizziness, headache, or throat irritation.

Side effects of Duexis that are different from Mobic include stomach pain, constipation, heartburn, vomiting, blurred vision, changes in color vision, or back pain.

Side effects of Mobic that are different from Duexis include drowsiness, nervousness, runny or stuffy nose, or skin rash.

Both Duexis and Mobic may interact with blood thinners or cold, allergy, or pain medicines that contain nonsteroidal anti-inflammatory drugs (NSAIDs).

Duexis may also interact with antidepressants.

Mobic may also interact with cyclosporine, lithium, diuretics (water pills), glyburide, methotrexate, steroids, or ACE inhibitors.

What Are Possible Side Effects of Duexis?

Common side effects of Duexis include:

  • stomach pain,
  • upset stomach,
  • constipation,
  • diarrhea,
  • bloating,
  • gas,
  • heartburn,
  • nausea,
  • vomiting,
  • dizziness,
  • headache,
  • throat irritation,
  • blurred vision,
  • changes in color vision, or
  • back pain.

Duexis can cause serious or fatal side effects including:

What Are Possible Side Effects of Mobic?

Common side effects of Mobic include:

  • injection site reactions (redness, itching, pain, bruising, swelling, or bleeding),
  • headache,
  • suffy nose,
  • sinus pain, or
  • stomach pain.

Tell your doctor if you have serious side effects of Mobic including:

  • stomach upset,
  • nausea,
  • drowsiness,
  • diarrhea,
  • bloating,
  • gas,
  • dizziness,
  • nervousness,
  • headache,
  • runny or stuffy nose,
  • sore throat, or
  • skin rash.

Tell your doctor if less common but serious side effects of Mobic occur including:

What Is Duexis?

Duexis (ibuprofen and famotidine) is a combination of a nonsteroidal anti-inflammatory drug (NSAID) and a histamine H2-receptor antagonist used to treat signs and symptoms of rheumatoid arthritis and osteoarthritis and to decrease the risk of developing upper gastrointestinal ulcers.

What Is Mobic?

Mobic (meloxicam) is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain or inflammation caused by arthritis. Mobic is available in generic form.


The term arthritis refers to stiffness in the joints. See Answer

What Drugs Interact With Duexis?

Duexis may interact with ACE-inhibitors. Duexis contains ibuprofen and may interact with anticoagulant medication such as Warfarin (Coumadin). Tell your doctor all medications you use. Duexis should not be given to women in late stages of pregnancy. There is potential for adverse reactions in nursing infants; consult your doctor before breastfeeding.

What Drugs Interact With Mobic?

Do not take Mobic right before or after a heart surgery called a "coronary artery bypass graft (CABG)."

Avoid taking Mobic after a recent heart attack, unless your healthcare provider tells you to. You may have an increased risk of another heart attack if you take NSAIDs after a recent heart attack.

How Should Duexis Be Taken?

Duexis is dosed as 800 mg/26.6 mg tablets, taken orally, three times per day.

How Should Mobic Be Taken?

Carefully consider the potential benefits and risks of MOBIC and other treatment options before deciding to use Mobic. Use the lowest effective dosage for the shortest duration consistent with individual patient treatment goals.


What Is Rheumatoid Arthritis (RA)? Symptoms, Treatment, Diagnosis See Slideshow

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Horizon Pharma USA, Inc. Duexis Product Information.
Dailymed. Mobic Product Information.

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