Duobrii vs. Enstilar

Are Duobrii and Enstilar the Same Thing?

Duobrii (halobetasol propionate and tazarotene) Lotion and Enstilar (calcipotriene and betamethasone dipropionate) Foam, 0.005%/0.064%, are used for the topical treatment of plaque psoriasis in adults.

Duobrii and Enstilar both contain a corticosteroid. Duobrii also contains a retinoid and Enstilar also contains a vitamin D analog.

Side effects of Duobrii and Enstilar that are similar include application site reactions (irritation, redness, infected hair follicles, loss of skin color).

Side effects of Duobrii that are different from Enstilar include contact dermatitis, thinning skin, skin abrasions, rash, stretch marks, and skin peeling.

Side effects of Enstilar that are different from Duobrii include high blood calcium levels, hives, and worsening of psoriasis.

Duobrii may interact with corticosteroids taken by mouth or injection and other products used on your skin that contain corticosteroids.

Enstilar may interact with other drugs.

What Are Possible Side Effects of Duobrii?

Common side effects of Duobrii include:

  • contact dermatitis,
  • application site pain,
  • infected hair follicles,
  • thinning skin,
  • skin abrasions,
  • rash,
  • stretch marks, and
  • skin peeling

What Are Possible Side Effects of Enstilar?

Common side effects of Enstilar include:

  • application site reactions (irritation, redness, infected hair follicles, loss of skin color),
  • high blood calcium levels,
  • hives, and
  • worsening of psoriasis

What Is Duobrii?

Duobrii (halobetasol propionate and tazarotene) Lotion is a combination of a corticosteroid and a retinoid indicated for the topical treatment of plaque psoriasis in adults.

What Is Enstilar?

Enstilar (calcipotriene and betamethasone dipropionate) Foam, 0.005%/0.064%, is a combination a vitamin D analog and a corticosteroid, indicated for the topical treatment of plaque psoriasis in patients 18 years of age and older.

SLIDESHOW

Types of Psoriasis: Medical Pictures and Treatments See Slideshow

What Drugs Interact With Duobrii?

Duobrii Lotion may interact with corticosteroids taken by mouth or injection, or other products used on your skin that contain corticosteroids. Tell your doctor all medications and supplements you use. Duobrii Lotion is not recommended for use during pregnancy; it may harm a fetus. A negative result for pregnancy should be obtained within 2 weeks prior to Duobrii Lotion therapy, which should begin during menstruation. Females of reproductive potential are advised to use effective contraception during treatment with Duobrii Lotion. It is unknown if Duobrii passes into breast milk.

What Drugs Interact With Enstilar?

Enstilar may interact with other drugs. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant before using Enstilar. Corticosteroids are known to cause harm to a fetus. Corticosteroids taken orally pass into breast milk; it is unknown if the topically applied medications in Enstilar would absorb systemically and pass into breast milk. Consult your doctor before breastfeeding.

How Should Duobrii Be Taken?

Apply a thin layer dose of Duobrii Lotion to the affected areas once daily.

How Should Enstilar Be Taken?

Apply a dose of Enstilar Foam to affected area(s) once daily for up to 4 weeks.

QUESTION

Psoriasis causes the top layer of skin cells to become inflamed and grow too quickly and flake off. See Answer

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References
FDA. Duobrii Product Information

https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/209354s000lbl.pdf

Leo Pharma. Enstilar Product Information.

www.enstilar.com/?

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