Dupixent vs. Advair Diskus

Dupixent (dupilumab) injection and Advair Diskus (fluticasone and salmeterol oral inhaler) are used to treat asthma.

Dupixen is also used to treat adult patients with moderate-to-severe atopic dermatitis whose disease is not adequately controlled with topical prescription therapies or when those therapies are not advisable. Dupixent can be used with or without topical corticosteroids.

Advair Diskus is also used to treat chronic bronchitis, including COPD associated with chronic bronchitis.

Dupixent and Advair Diskus belong to different drug classes. Dupixent is aninterleukin-4 receptor alpha-antagonist and Advair Diskus is a combination of a corticosteroid and a beta2-adrenergic bronchodilator.

Side effects of Dupixent that are different from Advair Diskus include injection site reactions, pink eye (conjunctivitis), swollen or puffy eyelids, oral herpes, inflammation of the cornea (keratitis), eye itching, other herpes simplex virus infection, and dry eye.

Side effects of Advair Diskus that are different from Dupixent include upper respiratory tract infections, headaches, dizziness, nausea, vomiting, stomach upset, diarrhea, yeast infections of the mouth or throat (oral thrush), sore throat, dry mouth/nose/throat, stuffy nose, sinus pain, cough, hoarseness or deepened voice, and musculoskeletal pain.

Dupixent may interact with "live" vaccines, warfarin, and cyclosporine.

Advair Diskus may interact with amiodarone, diuretics (water pills), HIV medicines, MAO inhibitors, antidepressants, antibiotics, antifungal medications, and beta-blockers.

Common side effects of Dupixent include:

• injection site reactions,
• pink eye (conjunctivitis),
• swollen or puffy eyelids,
• oral herpes,
• inflammation of the cornea (keratitis),
• eye itching,
• other herpes simplex virus infection, and
• dry eye.

Common side effects of Advair Diskus include:

• upper respiratory tract infections,
• headaches,
• dizziness,
• nausea,
• vomiting,
• stomach upset,
• diarrhea,
• yeast infections of the mouth or throat (oral thrush),
• sore throat,
• dry mouth/nose/throat,
• stuffy nose,
• sinus pain,
• cough,
• sore throat,
• hoarseness or deepened voice, and
• musculoskeletal pain.

Dupixent (dupilumab) injection is aninterleukin-4 receptor alpha-antagonist indicated for the treatment of adult patients with moderate-to-severe atopic dermatitis whose disease is not adequately controlled with topical prescription therapies or when those therapies are not advisable. Dupixent can be used with or without topical corticosteroids.

Advair Diskus (fluticasone and salmeterol oral inhaler) is a combination of a corticosteroid and a beta2-adrenergic bronchodilator used to treat asthma and chronic bronchitis, including COPD associated with chronic bronchitis. Advair Diskus is used in patients whose symptoms are not adequately controlled on a long-term asthma control medication, since one of the active ingredients in salmeterol is LABA, which has been linked to asthma-related deaths. Advair Diskus should not be used to treat acute episodes of asthma or COPD. Advair Diskus is available in generic form.

Dupixent may interact with:

• "live" vaccines
• warfarin, or
• cyclosporine
  
   

Tell your doctor all medications and supplements you use and all vaccines you recently received.

Advair Diskus may interact with amiodarone, diuretics (water pills), HIV medicines, MAO inhibitors, antidepressants, antibiotics, antifungal medications, or beta-blockers. Tell your doctor all medications and supplements you use. There have not been adequate studies of salmeterol in pregnant women. Fluticasone and salmeterol use by pregnant women should be avoided unless the potential benefit justifies the potential unknown risk to the fetus. Advair Diskus is secreted in breast milk. Consult your doctor before breastfeeding.

Our Advair Diskus Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

The recommended dose of Dupixent is an initial dose of 600 mg (two 300 mg injections in different injection sites), followed by 300 mg given every other week.

For patients aged 12 years and older, the dosage of Advair Diskus is 1 inhalation twice daily, approximately 12 hours apart.