Are Dupixent and Xolair the Same Thing?
Dupixent (dupilumab) injection and Xolair (omalizumab) are monoclonal antibodies used to treat moderate to severe asthma.
Dupixent is also used to treat adult patients with moderate-to-severe atopic dermatitis whose disease is not adequately controlled with topical prescription therapies or when those therapies are not advisable. Dupixent can be used with or without topical corticosteroids.
Side effects of Dupixent and Xolair that are similar include injection site reactions (itching, redness, stinging, pain, bruising, warmth, burning, or swelling).
Side effects of Dupixent that are different from Xolair include pink eye (conjunctivitis), swollen or puffy eyelids, oral herpes, inflammation of the cornea (keratitis), eye itching, other herpes simplex virus infection, and dry eye.
Side effects of Xolair that are different from Dupixent include headache, tired feeling, joint or muscle pain, dizziness, ear pain, hair loss, sore throat, cold symptoms, itching or skin rash, and leg or arm pain.
Dupixent may interact with "live" vaccines, warfarin, and cyclosporine.
Xolair may interact with allergy shots.
What Are Possible Side Effects of Dupixent?
Common side effects of Dupixent include:
- injection site reactions,
- pink eye (conjunctivitis),
- swollen or puffy eyelids,
- oral herpes,
- inflammation of the cornea (keratitis),
- eye itching,
- other herpes simplex virus infection, and
- dry eye.
What Are Possible Side Effects of Xolair?
Common side effects of Xolair include:
- headache,
- tired feeling,
- joint or muscle pain,
- dizziness,
- ear pain,
- hair loss,
- sore throat,
- cold symptoms,
- itching or skin rash,
- injection site reactions (itching, redness, stinging, pain, bruising, warmth, burning, or swelling), or
- leg or arm pain.
Tell your doctor if you have serious side effects of Xolair including unusual lumps/growths/moles.
SLIDESHOW
What Is Asthma? Symptoms, Causes, and Treatments See SlideshowWhat Is Dupixent?
Dupixent (dupilumab) injection is aninterleukin-4 receptor alpha-antagonist indicated for the treatment of adult patients with moderate-to-severe atopic dermatitis whose disease is not adequately controlled with topical prescription therapies or when those therapies are not advisable. Dupixent can be used with or without topical corticosteroids.
What Is Xolair?
Xolair (omalizumab) is an antibody that helps decrease allergic responses in the body used to treat moderate to severe asthma that is caused by allergies in adults and children who are at least 12 years old. Xolair is usually given after other asthma medications have been tried without successful treatment of symptoms.
What Drugs Interact With Dupixent?
Dupixent may interact with:
- "live" vaccines
- warfarin, or
- cyclosporine
What Drugs Interact With Xolair?
Before using Xolair, tell your doctor if you are receiving allergy shots. There may be other drugs that can interact with Xolair. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Xolair should be used only when prescribed during pregnancy. It is not known whether this drug passes into breast milk. Consult your doctor before breastfeeding.
How Should Dupixent be Taken?
The recommended dose of Dupixent is an initial dose of 600 mg (two 300 mg injections in different injection sites), followed by 300 mg given every other week.
From 
Asthma and Allergy Resources
Featured Centers
Health Solutions From Our Sponsors
All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).
Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.
Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.
The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.
As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.
Any missing drug warnings or information does not in any way guarantee the safety, effectiveness, or the lack of adverse effects of any drug. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.
If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.
You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.
https://www.dupixent.com
Genentech. Xolair Product Information.
www.xolair.com/?