Reviewed on 6/11/2021
Other Name(s):

Ambetan, Civet-Cat Fruit, Civet Fruit, Common Durian, Doerian, Dulian, Duren, Durian Kampong, Durian Puteh, Durianbaum, Durião, Durio zibethinus, Durión, Du-Yin, Kadu, Liu Lian, Nirpanas, Rian, Sâu Riêng, Stinkfrucht, Stinkvrucht, Thourièn, Thu-Réén, Thurian, Zibetbaum.


Durian is the fruit of a certain tree. The term durian can also be used to refer to the tree itself. The fruit, bark, and leaves of the durian tree are used as medicine.

People take durian by mouth for fever, swelling, high blood pressure, jaundice, malaria, parasites, and to increase sexual desire.

Durian is applied to the skin to treat skin diseases and reduce swelling.

How does it work?

Durian might benefit the heart and blood circulation. It might lower levels of cholesterol. It might also lower levels of a blood protein that helps form clots.


Next to red peppers, you can get the most vitamin C from ________________. See Answer

Uses & Effectiveness

Insufficient Evidence to Rate Effectiveness for...

  • Fever.
  • High blood pressure.
  • Jaundice.
  • Malaria.
  • Sexual desire.
  • Skin wounds.
  • Other conditions.
More evidence is needed to rate the effectiveness of durian for these uses.

Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).

Side Effects

It is not known if durian is safe. Eating durian fruit might cause stomach discomfort, gas, diarrhea, vomiting, or allergic reactions in some people. Eating durian seeds might cause shortness of breath.


Vitamin D Deficiency: How Much Vitamin D Is Enough? See Slideshow

Special Precautions & Warnings

Pregnancy and breast-feeding: Not enough is known about the use of durian during pregnancy and breast-feeding. Stay on the safe side and avoid use.

Diabetes: There is concern that durian might make diabetes worse. Eating durian seems to increase blood sugar levels more than other fruits such as bananas or mangos.


AlcoholInteraction Rating: Moderate Be cautious with this combination.Talk with your health provider.

The body breaks down the alcohol to get rid of it. Durian might decrease how fast the body breaks down alcohol. Drinking alcohol and taking durian might cause adverse effects such as a pounding headache, vomiting, flushing, and other unpleasant reactions. Don't drink any alcohol if you are taking durian.

Medications for diabetes (Antidiabetes drugs)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.

Durian might increase blood sugar. Diabetes medications are used to lower blood sugar. Taking durian along with diabetes medications might interfere with the effects of diabetes medications. Monitor your blood sugar closely. The dose of your diabetes medication might need to be changed.

Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.

Before taking durian, talk with your healthcare professional if you take these or any other medications.


The appropriate dose of durian depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for durian. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

FDA Logo

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Health Solutions From Our Sponsors


Berry, S. K. Cycloproprene fatty acid in some Malaysian edible seeds and nuts. I Durian (Durio zibethinus, Murr.). Lipids 1981;15:452.

Haruenkit, R., Poovarodom, S., Leontowicz, H., Leontowicz, M., Sajewicz, M., Kowalska, T., Delgado-Licon, E., Rocha-Guzman, N. E., Gallegos-Infante, J. A., Trakhtenberg, S., and Gorinstein, S. Comparative study of health properties and nutritional value of durian, mangosteen, and snake fruit: experiments in vitro and in vivo. J Agric Food Chem 2007;55(14):5842-5849. View abstract.

Leisner, J. J., Vancanneyt, M., Rusul, G., Pot, B., Lefebvre, K., Fresi, A., and Tee, L. K. Identification of lactic acid bacteria constituting the predominating microflora in an acid-fermented condiment (tempoyak) popular in Malaysia. Int J Food Microbiol 1-22-2001;63(1-2):149-157. View abstract.

Leisner, J. J., Vancanneyt, M., Van der, Meulen R., Lefebvre, K., Engelbeen, K., Hoste, B., Laursen, B. G., Bay, L., Rusul, G., De Vuyst, L., and Swings, J. Leuconostoc durionis sp. nov., a heterofermenter with no detectable gas production from glucose. Int J Syst Evol Microbiol 2005;55(Pt 3):1267-1270. View abstract.

Leontowicz, H., Leontowicz, M., Haruenkit, R., Poovarodom, S., Jastrzebski, Z., Drzewiecki, J., Ayala, A. L., Jesion, I., Trakhtenberg, S., and Gorinstein, S. Durian (Durio zibethinus Murr.) cultivars as nutritional supplementation to rat's diets. Food Chem Toxicol 2008;46(2):581-589. View abstract.

Leontowicz, M., Leontowicz, H., Jastrzebski, Z., Jesion, I., Haruenkit, R., Poovarodom, S., Katrich, E., Tashma, Z., Drzewiecki, J., Trakhtenberg, S., and Gorinstein, S. The nutritional and metabolic indices in rats fed cholesterol-containing diets supplemented with durian at different stages of ripening. Biofactors 2007;29(2-3):123-136. View abstract.

Maninang JS, Lizada, MCC, Gemma, H. Inhibition of aldehyde dehydrogenase enzyme by Durian (Durio zibethinus Murray) fruit extract. Food Chem 2009;117(2):352-355.

Mohd Adnan, A. F. and Tan, I. K. Isolation of lactic acid bacteria from Malaysian foods and assessment of the isolates for industrial potential. Bioresour Technol 2007;98(7):1380-1385. View abstract.

Nititham, S., Komindr, S., and Nichachotsalid, A. Phytate and fiber content in Thai fruits commonly consumed by diabetic patients. J Med Assoc Thai 2004;87(12):1444-1446. View abstract.

Ogle, C. W. and Teh, Y. F. Durian and alcohol. A preliminary report. Singapore Med J 1969;10(4):288-290. View abstract.

Olivieri, J., Quiliquini-Chambard, A. M., and Hauser, C. Allergy to durian. Allergy 2002;57(3):263. View abstract.

Roongpisuthipong, C., Banphotkasem, S., Komindr, S., and Tanphaichitr, V. Postprandial glucose and insulin responses to various tropical fruits of equivalent carbohydrate content in non-insulin-dependent diabetes mellitus. Diabetes Res Clin Pract 1991;14(2):123-131. View abstract.

Rudiyansyah and Garson, M. J. Secondary metabolites from the wood bark of Durio zibethinus and Durio kutejensis. J Nat Prod 2006;69(8):1218-1221. View abstract.

Singh, P. Journal of the Malaya Branch British Medical Association 1941;5(1):62-63.

Stanton, W. R. The chemical composition of some tropical food plants VI: Durian. Tropical Science 1966;8(1):6-10.

Toledo, F., Arancibia-Avila, P., Park, Y. S., Jung, S. T., Kang, S. G., Heo, B. G., Drzewiecki, J., Zachwieja, Z., Zagrodzki, P., Pasko, P., and Gorinstein, S. Screening of the antioxidant and nutritional properties, phenolic contents and proteins of five durian cultivars. Int J Food Sci Nutr 2008;1-13. View abstract.

Health Solutions From Our Sponsors