Durysta

Last updated on RxList: 1/22/2021
Durysta Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

What Is Durysta?

Durysta (bimatoprost implant) is a prostaglandin analog used to reduce intraocular pressure (IOP) in patients with open angle glaucoma (OAG) or ocular hypertension (OHT).

What Are Side Effects of Durysta?

Side effects of Durysta include:

Dosage for Durysta

The dose of Durysta is one intracameral implant containing bimatoprost 10 mcg, in the drug delivery system.

Durysta In Children

Safety and effectiveness of Durysta in pediatric patients have not been established.

What Drugs, Substances, or Supplements Interact with Durysta?

Durysta may interact with other medicines.

Tell your doctor all medications and supplements you use.

Durysta During Pregnancy and Breastfeeding

Tell your doctor if you are pregnant or plan to become pregnant before using Durysta; it is unknown how it would affect a fetus. It is unknown if Durysta passes into breast milk. Consult your doctor before breastfeeding.

Additional Information

Our Durysta (bimatoprost implant), for Intracameral Administration Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

QUESTION

What causes dry eyes? See Answer
Durysta Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • worsening eye pain or redness;
  • vision changes;
  • increased sensitivity to light; or
  • signs of eye infection--puffy eyelids, eye redness, severe discomfort, crusting or drainage, vision loss.

Common side effects may include:

  • eye redness or a blood spot on the white of your eye;
  • eye pain;
  • feeling like something is in your eye;
  • eye dryness or irritation;
  • blurred vision, inflammation of the iris;
  • headache;
  • increased pressure inside the eye; or
  • a loss of cells on the inner layer of your cornea.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Durysta (Bimatoprost Implant)

SLIDESHOW

Pink Eye (Conjunctivitis) Symptoms, Causes, Treatments See Slideshow
Durysta Professional Information

SIDE EFFECTS

The following clinically significant adverse reactions are described elsewhere in labeling:

  • Implant migration [see CONTRAINDICATIONS]
  • Hypersensitivity [see CONTRAINDICATIONS]
  • Corneal adverse reactions [see WARNINGS AND PRECAUTIONS]
  • Macular edema [see WARNINGS AND PRECAUTIONS]
  • Intraocular inflammation [see WARNINGS AND PRECAUTIONS]
  • Pigmentation [see WARNINGS AND PRECAUTIONS]
  • Endophthalmitis [see WARNINGS AND PRECAUTIONS]

Clinical Trials Experience

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.

The most common ocular adverse reaction observed in two randomized, active-controlled clinical trials with DURYSTA in patients with OAG or OHT was conjunctival hyperemia, which was reported in 27% of patients. Other common ocular adverse reactions reported in 5-10% of patients were foreign body sensation, eye pain, photophobia, conjunctival hemorrhage, dry eye, eye irritation, intraocular pressure increased, corneal endothelial cell loss, vision blurred, and iritis. Ocular adverse reactions occurring in 1-5% of patients were anterior chamber cell, lacrimation increased, corneal edema, aqueous humor leakage, iris adhesions, ocular discomfort, corneal touch, iris hyperpigmentation, anterior chamber flare, anterior chamber inflammation, and macular edema. The following additional adverse drug reactions occurred in less than 1% of patients: hyphema, iridocyclitis, uveitis, corneal opacity, product administered at inappropriate site, corneal decompensation, cystoid macular edema, and drug hypersensitivity.

The most common nonocular adverse reaction was headache, which was observed in 5% of patients.

Read the entire FDA prescribing information for Durysta (Bimatoprost Implant)

© Durysta Patient Information is supplied by Cerner Multum, Inc. and Durysta Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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