Dyspnea: Difficult or labored breathing; shortness of breath. Dyspnea is a sign of serious disease of the airway, lungs, or heart. The onset of dyspnea should not be ignored; it is reason to seek medical attention. SLIDESHOW COPD Foods to Boost Your Health - COPD Diet Tips See Slideshow From Lung Disease/COPD Resources How Extensive Stage SCLC Is Diagnosed Featured Centers Good and Bad Foods for PsoriasisVideo: Getting Personal on Life With MS Health Solutions From Our Sponsors Shot-Free MS Treatment Your Child and COVID-19