Definition of Dystonia, dopa-responsive (DRD)

Reviewed on 6/3/2021

Dystonia, dopa-responsive (DRD): A condition that typically begins in childhood or adolescence with progressive difficulty in walking and, in some cases, spasticity, and can be successfully treated with drugs.

Segawa dystonia is an important variant of DRD. In Segawa dystonia, the symptoms fluctuate during the day from relative mobility in the morning to increasing disability in the afternoon and evening and after exercise.

DRD may not only be rare but also rarely diagnosed since it mimics some forms of cerebral palsy.

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