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E. Coli 0157:H7 (cont.)

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What is the treatment for E. coli 0157:H7?

Treatment for E. coli 0157:H7 depends on the severity of the disease.

Patients, especially healthy adults, often require no treatment for E. coli O157:H7 since many infections are self-limited. Moreover, for the acute diarrheal illness, antibiotics have not proven useful. In fact, some studies have shown that antibiotics may increase the chances of developing HUS (up to 17-fold). This effect is thought to occur because the antibiotic damages the bacteria, causing them to release even more toxin. Most investigators suggest antibiotic use only if a patient is septic, that is, there is evidence that the bacterium has spread to parts of the body other than the intestine. In addition, use of atropine and diphenoxylate (Lomotil), drugs that are commonly used to control diarrhea, also may increase symptoms and trigger complications.

In summary, mild infections are treated with the following:

  • Rest
  • Fluid intake
  • Rarely, antibiotics

Treatment for severe symptoms of infection and its complications may include:

  1. Treatment in an Intensive care unit (ICU)
  2. Intravenous fluids and electrolytes
  3. Red blood cell transfusion(s)
  4. Platelet transfusion
  5. Plasma exchange
  6. Kidney dialysis
  7. Medications for high blood pressure
  8. Medications for seizures
  9. Kidney transplantation
Medically Reviewed by a Doctor on 9/25/2017

Source: MedicineNet.com
https://www.medicinenet.com/e_coli__0157h7/article.htm

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